Insulin resistance and selection of antihypertensive drug. Effects of antihypertensive drug on insulin sensitivity.
نویسندگان
چکیده
منابع مشابه
Drug interactions of antihypertensive agents
Adverse drug-drug interactions may occur when a major therapeutic mechanism of one drug class (such as bradycardia with a beta blocker) is excessively exaggerated by the addition of another heart-rate slowing antihypertensive, such as verapamil. The most important interactions at the molecular level are those of the hepatic enzyme, cytochrome (CYP) 3A4. A classic example is the inhibitory effec...
متن کاملAppraisal of antihypertensive drug therapy.
SUMMARY Four completed prospective studies of drug-treated and control hypertensives utilizing double blind ran-domized protocols are reviewed for the purpose of evaluating the evidence on which the present therapeutic crusade is based. Patients studied were predominantly male, observed for short period, had complications or died at young age, had high incidence of previous target organ vascula...
متن کاملIndividualization of Antihypertensive Drug Treatment
Antihypertensive drug classes are usually classified as 1st, 2nd, 3rd, and 4th or 5th choice to help physicians select the drug most suitable for treatment initiation among the very many classes available to lower blood pressure (BP) in patients with a BP elevation. However, this approach was appropriate decades ago when several drugs had inconveniences that made their use in monotherapy inadvi...
متن کاملDifferential effects of antihypertensive drug therapy on arterial compliance.
Although vascular compliance, deltaV/deltaP, is abnormal in essential hypertension and can be improved by antihypertensive drug therapy, it is not clear whether drug-induced changes in compliance are attributable solely to lower achieved blood pressure (BP), and thus equally likely with different drugs possessing similar antihypertensive efficacy. Therefore, we used computerized arterial pulse ...
متن کاملPersistence to antihypertensive drug classes
The aim was to study persistence to, and switching between, antihypertensive drug classes and to determine factors associated with poor persistence.This was an observational cohort study. The Swedish Primary Care Cardiovascular Database includes data from medical records, socioeconomic data, filled prescriptions, and hospitalizations from national registries for 75,000 patients with hypertensio...
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ژورنال
عنوان ژورنال: Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics
سال: 1996
ISSN: 1882-8272,0388-1601
DOI: 10.3999/jscpt.27.381